Coinbase Global (COIN +9.24%) is positioning itself at the forefront of a burgeoning digital economy driven by artificial intelligence. The exchange believes the next phase of cryptocurrency adoption will be defined by AI agents autonomously transacting with one another. Data from Chainalysis highlights the momentum behind this shift, recording over 100 million agent-led transactions on Coinbase’s Base blockchain during the first quarter of 2026. Brian Armstrong, CEO of Coinbase, has expressed a bold outlook, suggesting that these autonomous agents will eventually surpass human users in total transaction volume. While Base is currently a leader in this space, significant activity is also being recorded on Ethereum (ETH -1.69%) and Solana (SOL -1.10%). As the concept of 'agentic payments'—automated financial transfers executed by AI—moves from theory to reality, these blockchain networks are becoming the essential infrastructure for an emerging machine-to-machine economy.